Jump to main content
Jump to site search


Copper-catalyzed three-component phosphorylation–peroxidation of alkenes

Author affiliations

Abstract

A copper-catalyzed phosphorylation–peroxidation of alkenes has been developed. The three-component protocol provides practical access to multisubstituted β-phosphoryl peroxides by the reactions of P(O)–H compounds, alkenes and tert-butyl hydroperoxide (TBHP). The obtained β-phosphoryl peroxides can be applied to the synthesis of β-phosphoryl epoxides by using lithium bis(trimethylsilyl)amide (LHMDS) as a base.

Graphical abstract: Copper-catalyzed three-component phosphorylation–peroxidation of alkenes

Back to tab navigation

Supplementary files

Publication details

The article was received on 22 Nov 2017, accepted on 20 Dec 2017 and first published on 21 Dec 2017


Article type: Research Article
DOI: 10.1039/C7QO01045A
Citation: Org. Chem. Front., 2018, Advance Article
  •   Request permissions

    Copper-catalyzed three-component phosphorylation–peroxidation of alkenes

    Y. Chen, Y. Chen, S. Lu and Z. Li, Org. Chem. Front., 2018, Advance Article , DOI: 10.1039/C7QO01045A

Search articles by author

Spotlight

Advertisements