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Total synthesis and absolute configuration reassignment of mollenines A and B

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Abstract

The first total synthesis of the indole alkaloids mollenines A and B with the diketomorpholine skeleton has been accomplished in 9 and 10 steps with an overall yield of 11.4% and 9.3%, respectively. The absolute stereochemistry of the two natural products was corrected.

Graphical abstract: Total synthesis and absolute configuration reassignment of mollenines A and B

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Publication details

The article was received on 30 Oct 2017, accepted on 16 Dec 2017 and first published on 18 Dec 2017


Article type: Research Article
DOI: 10.1039/C7QO00985B
Citation: Org. Chem. Front., 2018, Advance Article
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    Total synthesis and absolute configuration reassignment of mollenines A and B

    M. Wang, T. Si, C. Ku, X. Li, Z. Li, H. Zhang and A. S. C. Chan, Org. Chem. Front., 2018, Advance Article , DOI: 10.1039/C7QO00985B

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