Issue 6, 2018

Total synthesis and absolute configuration reassignment of mollenines A and B

Abstract

The first total synthesis of the indole alkaloids mollenines A and B with the diketomorpholine skeleton has been accomplished in 9 and 10 steps with an overall yield of 11.4% and 9.3%, respectively. The absolute stereochemistry of the two natural products was corrected.

Graphical abstract: Total synthesis and absolute configuration reassignment of mollenines A and B

Supplementary files

Article information

Article type
Research Article
Submitted
30 Oct 2017
Accepted
16 Dec 2017
First published
18 Dec 2017

Org. Chem. Front., 2018,5, 954-957

Total synthesis and absolute configuration reassignment of mollenines A and B

M. Wang, T. Si, C. Ku, X. Li, Z. Li, H. Zhang and A. S. C. Chan, Org. Chem. Front., 2018, 5, 954 DOI: 10.1039/C7QO00985B

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