Issue 5, 2018
From the journal:

Organic Chemistry Frontiers

Enantioselective total synthesis of periconiasin A†

Zhixiong Zeng,a   Cheng Chena  and  Yandong Zhang ORCID logo *a  

* Corresponding authors

a Department of Chemistry and Key Laboratory for Chemical Biology of Fujian Province, iChEM, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, Fujian 361005, China
E-mail: ydzhang@xmu.edu.cn

Abstract

A concise, enantioselective total synthesis of periconiasin A, a hybrid natural product, has been achieved, featuring a ring closing metathesis (RCM) reaction and a Suzuki coupling to secure a (Z,E,E)-skipped triene system and an intramolecular Diels–Alder (IMDA) reaction to construct the challenging 6–9 fused ring system.

Graphical abstract: Enantioselective total synthesis of periconiasin A

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Article information

DOI
https://doi.org/10.1039/C7QO00952F
Article type
Research Article
Submitted
20 Oct 2017
Accepted
30 Nov 2017
First published
01 Dec 2017

Org. Chem. Front., 2018,5, 838-840

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Enantioselective total synthesis of periconiasin A

Z. Zeng, C. Chen and Y. Zhang, Org. Chem. Front., 2018, 5, 838 DOI: 10.1039/C7QO00952F

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