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Issue 4, 2018
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Cobalt-catalyzed cross-dehydrogenative coupling of imidazo[1,2-a]pyridines with isochroman using molecular oxygen as the oxidant

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Abstract

A cobalt-catalyzed cross-dehydrogenative coupling of 2-arylimidazo[1,2-a]pyridines with isochroman using molecular oxygen as the oxidant is reported. A broad range of 2-arylimidazo[1,2-a]pyridines reacted smoothly to afford the corresponding products in moderate to good yields. The advantages of this method are: inexpensive catalysts, environmentally benign conditions and operational convenience.

Graphical abstract: Cobalt-catalyzed cross-dehydrogenative coupling of imidazo[1,2-a]pyridines with isochroman using molecular oxygen as the oxidant

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Publication details

The article was received on 26 Sep 2017, accepted on 24 Oct 2017 and first published on 26 Oct 2017


Article type: Research Article
DOI: 10.1039/C7QO00875A
Citation: Org. Chem. Front., 2018,5, 577-581
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    Cobalt-catalyzed cross-dehydrogenative coupling of imidazo[1,2-a]pyridines with isochroman using molecular oxygen as the oxidant

    Q. Yang, S. Li and J. (. Wang, Org. Chem. Front., 2018, 5, 577
    DOI: 10.1039/C7QO00875A

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