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Selective and Rapid Detection of Ascorbic Acid by Cobalt Oxyhydroxide-Based Two-Photon Fluorescent Nano-Platform

Abstract

The development of efficient and easy fabricated approach to detect ascorbic acid (AA) is of physiological and pathological significance. In this work, a two-photon sensor platform which is constituted with 1,8-naphthalimide-based fluorophore and CoOOH nanosheets was designed in which the blue two-photon fluorescence of fluorophore was suppressed to a remarkable extent via a FRET progress between CoOOH nanosheets and fluorophore. The fluorescence inhibition could be removed through the specific reaction of CoOOH and AA.. Based on this feature, we have demonstrated the prominent sensing performance of the sensor platform, including excellent two-photon induced fluorescence properties, convenient fabrication pathway, specific response to AA, wider linear range and the high stability. This fluorescent assay is capable to detect AA in living cells and is potential for further application such as AA associated disease diagnosis.

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Publication details

The article was received on 03 Jan 2018, accepted on 09 Feb 2018 and first published on 09 Feb 2018


Article type: Research Article
DOI: 10.1039/C8QI00003D
Citation: Inorg. Chem. Front., 2018, Accepted Manuscript
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    Selective and Rapid Detection of Ascorbic Acid by Cobalt Oxyhydroxide-Based Two-Photon Fluorescent Nano-Platform

    Q. Han, H. Yang, S. Wen, H. Jiang, L. Wang and W. Liu, Inorg. Chem. Front., 2018, Accepted Manuscript , DOI: 10.1039/C8QI00003D

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