Stability of Diels–Alder photoadducts in macromolecules†
Abstract
We explore the stability of o-quinodimethane-based ligation points generated by a popular photo-induced Diels–Alder reaction, assessing their ability to withstand challenging environments. Our molecular assessment includes size-exclusion chromatography as well as high resolution electrospray ionization mass spectrometry (SEC-HR ESI MS), finding that their stability is dependent on the macromolecular chain length.