Issue 37, 2018
From the journal:

Polymer Chemistry

Antibacterial activity of cationic polymers: side-chain or main-chain type?†

Jiangna Guo, ORCID logo ‡a   Jing Qin, ORCID logo ‡a   Yongyuan Ren, ORCID logo a   Bin Wang, ORCID logo b   Hengqing Cui, ORCID logo b   Yingying Ding, ORCID logo c   Hailei Mao ORCID logo *c  and  Feng Yan ORCID logo *a  

* Corresponding authors

a Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application, Department of Polymer Science and Engineering, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, China
E-mail: fyan@suda.edu.cn

b Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China

c Department of Anesthesiology and Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China
E-mail: mao.hailei@zs-hospital.sh.cn

Abstract

Imidazolium (Im), quaternary ammonium (Qa), and 1,4-diazabicyclo[2.2.2]octane-1,4-diium (DABCO-diium) cation-based small molecule cationic compounds, and their corresponding side-chain/main-chain cationic polymers were synthesized. The antibacterial activities of the three kinds of synthesized antibacterial agents decreased in the order: main-chain cationic polymers > side-chain cationic polymers > small molecule cationic compounds.

Graphical abstract: Antibacterial activity of cationic polymers: side-chain or main-chain type?

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Article information

DOI
https://doi.org/10.1039/C8PY00665B
Article type
Communication
Submitted
01 May 2018
Accepted
15 Aug 2018
First published
20 Aug 2018

Polym. Chem., 2018,9, 4611-4616

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Antibacterial activity of cationic polymers: side-chain or main-chain type?

J. Guo, J. Qin, Y. Ren, B. Wang, H. Cui, Y. Ding, H. Mao and F. Yan, Polym. Chem., 2018, 9, 4611 DOI: 10.1039/C8PY00665B

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