Jump to main content
Jump to site search

Issue 6, 2018
Previous Article Next Article

Visible-light-activated photoCORMs: rational design of CO-releasing organic molecules absorbing in the tissue-transparent window

Author affiliations

Abstract

To date, most known molecules that release carbon monoxide by the action of light are based on carbonyl complexes of metals. However, they suffer from several disadvantages, so the focus of this perspective is on photoactivatable metal-free CO precursors. The development and design of these systems from the starting point of deep-UV-absorbing hydrophobic molecules and leading to hydrophilic biocompatible visible-light-absorbing CO-releasing molecules (photoCORMs) is described with mechanistic details for several structural motifs. The possibilities of this development are not exhausted and here we discuss the design of new biologically interesting candidates.

Graphical abstract: Visible-light-activated photoCORMs: rational design of CO-releasing organic molecules absorbing in the tissue-transparent window

Back to tab navigation

Publication details

The article was received on 03 Mar 2018, accepted on 02 May 2018 and first published on 03 May 2018


Article type: Perspective
DOI: 10.1039/C8PP00096D
Citation: Photochem. Photobiol. Sci., 2018,17, 692-710
  •   Request permissions

    Visible-light-activated photoCORMs: rational design of CO-releasing organic molecules absorbing in the tissue-transparent window

    T. Slanina and P. Šebej, Photochem. Photobiol. Sci., 2018, 17, 692
    DOI: 10.1039/C8PP00096D

Search articles by author

Spotlight

Advertisements