Jump to main content
Jump to site search

Issue 23, 2018
Previous Article Next Article

Base-controlled Fe(Pc)-catalyzed aerobic oxidation of thiols for the synthesis of S–S and S–P(O) bonds

Author affiliations

Abstract

Fe(Pc)-Catalyzed aerobic oxidation of thiols for the synthesis of disulfides has been developed under mild reaction conditions. In addition, an aerobic oxidative cross-dehydrogenative coupling (CDC) reaction of thiols with P(O)–H compounds (H-phosphonates and H-phosphine oxide) for the formation of S–P(O) bonds has been demonstrated under the Fe(Pc) catalysis system with a base additive. Control experiments revealed that the use of a base (DIPA) in this system controls the synthetic pathways in which thiophosphates are formed.

Graphical abstract: Base-controlled Fe(Pc)-catalyzed aerobic oxidation of thiols for the synthesis of S–S and S–P(O) bonds

Back to tab navigation

Supplementary files

Publication details

The article was received on 17 Apr 2018, accepted on 17 May 2018 and first published on 17 May 2018


Article type: Communication
DOI: 10.1039/C8OB00908B
Citation: Org. Biomol. Chem., 2018,16, 4236-4242
  •   Request permissions

    Base-controlled Fe(Pc)-catalyzed aerobic oxidation of thiols for the synthesis of S–S and S–P(O) bonds

    H. Huang, J. Ash and J. Y. Kang, Org. Biomol. Chem., 2018, 16, 4236
    DOI: 10.1039/C8OB00908B

Search articles by author

Spotlight

Advertisements