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Total synthesis of incargranine A

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Abstract

Synthetic studies into the origins of the alkaloid incargranine A have resulted in the development of a four-step (longest linear sequence) total synthesis. This synthesis has been scaled-up to provide gram-scale quantities of material, which would alternatively require extraction of several metric-tons of dried-whole Chinese Trumpet-Creeper plants (Incarvillea mairei var. grandiflora).

Graphical abstract: Total synthesis of incargranine A

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Publication details

The article was received on 22 Mar 2018, accepted on 04 Apr 2018 and first published on 04 Apr 2018


Article type: Communication
DOI: 10.1039/C8OB00702K
Citation: Org. Biomol. Chem., 2018, Advance Article
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    Total synthesis of incargranine A

    P. D. Brown and A. L. Lawrence, Org. Biomol. Chem., 2018, Advance Article , DOI: 10.1039/C8OB00702K

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