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Issue 14, 2018
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Visualization of mercury(II) accumulation in vivo using bioluminescence imaging with a highly selective probe

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Abstract

Mercury is a highly toxic environmental pollutant that negatively affects human health. Thus, an in vivo method for noninvasive imaging of mercury(II) and visualization of its accumulation within living systems would be advantageous. Herein, we describe a reaction-based bioluminescent probe for detection of mercury(II) in vitro and accumulation in vivo. The application of this probe would help to shed light on the intricate contributions of mercury(II) to various physiological and pathological processes.

Graphical abstract: Visualization of mercury(ii) accumulation in vivo using bioluminescence imaging with a highly selective probe

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Publication details

The article was received on 14 Feb 2018, accepted on 13 Mar 2018 and first published on 13 Mar 2018


Article type: Communication
DOI: 10.1039/C8OB00398J
Citation: Org. Biomol. Chem., 2018,16, 2388-2392
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    Visualization of mercury(II) accumulation in vivo using bioluminescence imaging with a highly selective probe

    B. Ke, H. Chen, L. Ma, S. Zingales, D. Gong, D. Hu, L. Du and M. Li, Org. Biomol. Chem., 2018, 16, 2388
    DOI: 10.1039/C8OB00398J

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