Jump to main content
Jump to site search

Issue 15, 2018
Previous Article Next Article

Direct C4–H phosphonation of 8-hydroxyquinoline derivatives employing photoredox catalysis and silver catalysis

Author affiliations

Abstract

A simple and efficient protocol for the C4–H phosphonation of 8-hydroxyquinoline derivatives was developed under a photoredox/silver(I) cocatalysis system, providing a new approach to phosphonated 8-hydroxyquinoline derivatives. Note that the reaction did not occur at the C5 site, but regioselectively at an unusual C4 site. Moreover, the reaction proceeded smoothly under mild reaction conditions (a catalytic amount of silver salt and room temperature) with good functional group compatibility.

Graphical abstract: Direct C4–H phosphonation of 8-hydroxyquinoline derivatives employing photoredox catalysis and silver catalysis

Back to tab navigation

Supplementary files

Publication details

The article was received on 12 Feb 2018, accepted on 22 Mar 2018 and first published on 28 Mar 2018


Article type: Paper
DOI: 10.1039/C8OB00370J
Citation: Org. Biomol. Chem., 2018,16, 2753-2756
  •   Request permissions

    Direct C4–H phosphonation of 8-hydroxyquinoline derivatives employing photoredox catalysis and silver catalysis

    X. Su, F. Yang, Y. Wu and Y. Wu, Org. Biomol. Chem., 2018, 16, 2753
    DOI: 10.1039/C8OB00370J

Search articles by author

Spotlight

Advertisements