Jump to main content
Jump to site search

Issue 12, 2018
Previous Article Next Article

PhI(OAc)2-mediated dearomative C–N coupling: facile construction of the spiro[indoline-3,2′-pyrrolidine] skeleton

Author affiliations

Abstract

A facile construction of the spiro[indole-3,2′-pyrrolidine] skeleton, through diacetoxyiodobenzene (PIDA) mediated C–N bond-forming dearomatization of C3 sulfonamide linked indole derivatives, has been developed. A variety of spiro-indolepyrrolidines were obtained in moderate to excellent yields under mild conditions.

Graphical abstract: PhI(OAc)2-mediated dearomative C–N coupling: facile construction of the spiro[indoline-3,2′-pyrrolidine] skeleton

Back to tab navigation

Supplementary files

Publication details

The article was received on 09 Feb 2018, accepted on 01 Mar 2018 and first published on 02 Mar 2018


Article type: Communication
DOI: 10.1039/C8OB00343B
Citation: Org. Biomol. Chem., 2018,16, 2039-2042
  •   Request permissions

    PhI(OAc)2-mediated dearomative C–N coupling: facile construction of the spiro[indoline-3,2′-pyrrolidine] skeleton

    Y. Zhou, D. Li, S. Tang, H. Sun, J. Huang and Q. Zhu, Org. Biomol. Chem., 2018, 16, 2039
    DOI: 10.1039/C8OB00343B

Search articles by author

Spotlight

Advertisements