Jump to main content
Jump to site search

Issue 10, 2018
Previous Article Next Article

Palladium-catalyzed synthesis of quinolin-2(1H)-ones: the unexpected reactivity of azodicarboxylate

Author affiliations

Abstract

Quinolin-2(1H)-one is a useful structure unit present in a wide range of natural products and pharmaceuticals. A Pd(II)-catalyzed synthesis of quinolin-2(1H)-ones from quinoline N-oxides was developed with azodicarboxylates which act as both the activating agent and oxidant. The reaction proceeded under mild conditions and no protection against air and moisture was needed.

Graphical abstract: Palladium-catalyzed synthesis of quinolin-2(1H)-ones: the unexpected reactivity of azodicarboxylate

Back to tab navigation

Supplementary files

Publication details

The article was received on 24 Jan 2018, accepted on 12 Feb 2018 and first published on 12 Feb 2018


Article type: Communication
DOI: 10.1039/C8OB00199E
Citation: Org. Biomol. Chem., 2018,16, 1632-1635
  •   Request permissions

    Palladium-catalyzed synthesis of quinolin-2(1H)-ones: the unexpected reactivity of azodicarboxylate

    J. Peng, B. Chen, X. Qi, J. Ying and X. Wu, Org. Biomol. Chem., 2018, 16, 1632
    DOI: 10.1039/C8OB00199E

Search articles by author

Spotlight

Advertisements