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Direct synthesis of alkenyl iodides via indium-catalyzed iodoalkylation of alkynes with alcohols and aqueous HI

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Abstract

A convenient and efficient indium-catalyzed approach to synthesize alkenyl iodides has been developed through direct iodoalkylation of alkynes with alcohols and aqueous HI under mild conditions. This catalytic protocol offers an attractive approach for the synthesis of a diverse range of alkenyl iodides in good to excellent yields.

Graphical abstract: Direct synthesis of alkenyl iodides via indium-catalyzed iodoalkylation of alkynes with alcohols and aqueous HI

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Publication details

The article was received on 22 Jan 2018, accepted on 28 Mar 2018 and first published on 28 Mar 2018


Article type: Paper
DOI: 10.1039/C8OB00183A
Citation: Org. Biomol. Chem., 2018, Advance Article
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    Direct synthesis of alkenyl iodides via indium-catalyzed iodoalkylation of alkynes with alcohols and aqueous HI

    C. Wu, Z. Wang, Z. Hu, F. Zeng, X. Zhang, Z. Cao, Z. Tang, W. He and X. Xu, Org. Biomol. Chem., 2018, Advance Article , DOI: 10.1039/C8OB00183A

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