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Aromatically functionalized pseudo-crown ethers with unusual solvent response and enhanced binding properties

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Abstract

Conformational flexibility in the host's structure is often considered detrimental to its binding. Flexible pseudo-crown ethers with aromatic donor/acceptor groups at the chain ends, however, displayed enhanced binding affinity and selectivity, particularly when the direct binding interactions were compromised by unfavorable solvents.

Graphical abstract: Aromatically functionalized pseudo-crown ethers with unusual solvent response and enhanced binding properties

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Publication details

The article was received on 12 Jan 2018, accepted on 08 Feb 2018 and first published on 08 Feb 2018


Article type: Communication
DOI: 10.1039/C8OB00100F
Citation: Org. Biomol. Chem., 2018, Advance Article
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    Aromatically functionalized pseudo-crown ethers with unusual solvent response and enhanced binding properties

    X. Xing and Y. Zhao, Org. Biomol. Chem., 2018, Advance Article , DOI: 10.1039/C8OB00100F

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