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Issue 5, 2018
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Rhodium-catalyzed C7-alkylation of indolines with maleimides

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Abstract

A rhodium(III)-catalyzed direct cross-coupling reaction of indolines with maleimides via C–H bond activation was developed. This protocol displays good functional group tolerance, which offers a novel approach to access C7 modified indoline derivatives including maleimide analogues.

Graphical abstract: Rhodium-catalyzed C7-alkylation of indolines with maleimides

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Publication details

The article was received on 08 Dec 2017, accepted on 03 Jan 2018 and first published on 03 Jan 2018


Article type: Communication
DOI: 10.1039/C7OB03039H
Citation: Org. Biomol. Chem., 2018,16, 693-697
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    Rhodium-catalyzed C7-alkylation of indolines with maleimides

    C. Pan, Y. Wang, C. Wu and J. Yu, Org. Biomol. Chem., 2018, 16, 693
    DOI: 10.1039/C7OB03039H

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