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Issue 5, 2018
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Highly chemoselective intermolecular cross-benzoin reactions using an ad hoc designed novel N-heterocyclic carbene catalyst

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Abstract

The design of a novel N-heterocyclic carbene catalyst incorporating a bulky yet highly electron-deficient N-aryl substituent has allowed the development of an efficient protocol for the first highly chemoselective intermolecular benzoin condensations between two non-identical aromatic aldehydes.

Graphical abstract: Highly chemoselective intermolecular cross-benzoin reactions using an ad hoc designed novel N-heterocyclic carbene catalyst

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Publication details

The article was received on 05 Dec 2017, accepted on 04 Jan 2018 and first published on 10 Jan 2018


Article type: Paper
DOI: 10.1039/C7OB03005C
Citation: Org. Biomol. Chem., 2018,16, 780-786
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    Highly chemoselective intermolecular cross-benzoin reactions using an ad hoc designed novel N-heterocyclic carbene catalyst

    E. G. Delany and S. J. Connon, Org. Biomol. Chem., 2018, 16, 780
    DOI: 10.1039/C7OB03005C

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