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Issue 4, 2018
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A mild method for synthesizing carboxylic acids by oxidation of aldoximes using hypervalent iodine reagents

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Abstract

A mild oxidation method for the conversion of aldoximes to carboxylic acids was developed mediated by hypervalent iodine reagents. This method covers a wide range of functionalized aldoximes and proceeds under mild conditions, utilizing PhI(OH)OTs as an oxidant.

Graphical abstract: A mild method for synthesizing carboxylic acids by oxidation of aldoximes using hypervalent iodine reagents

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Publication details

The article was received on 21 Nov 2017, accepted on 02 Jan 2018 and first published on 02 Jan 2018


Article type: Communication
DOI: 10.1039/C7OB02858J
Citation: Org. Biomol. Chem., 2018,16, 541-544
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    A mild method for synthesizing carboxylic acids by oxidation of aldoximes using hypervalent iodine reagents

    A. Nakamura, H. Kanou, J. Tanaka, A. Imamiya, T. Maegawa and Y. Miki, Org. Biomol. Chem., 2018, 16, 541
    DOI: 10.1039/C7OB02858J

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