Jump to main content
Jump to site search


A Brønsted acid-promoted asymmetric intramolecular allylic amination of alcohols

Author affiliations

Abstract

Reported herein is a chiral Brønsted acid-catalyzed asymmetric intramolecular allylic amination reaction, allowing facile access to a range of biologically interesting chiral 2-substituted hydroquinolines in up to 90% yield and with up to 93% ee. Furthermore, a significant effect of an N-protecting group was observed in this asymmetric process.

Graphical abstract: A Brønsted acid-promoted asymmetric intramolecular allylic amination of alcohols

Back to tab navigation

Supplementary files

Publication details

The article was received on 22 Oct 2017, accepted on 06 Dec 2017 and first published on 07 Dec 2017


Article type: Communication
DOI: 10.1039/C7OB02599H
Citation: Org. Biomol. Chem., 2018, Advance Article
  •   Request permissions

    A Brønsted acid-promoted asymmetric intramolecular allylic amination of alcohols

    J. Zhou and H. Xie, Org. Biomol. Chem., 2018, Advance Article , DOI: 10.1039/C7OB02599H

Search articles by author

Spotlight

Advertisements