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Issue 25, 2018
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How can nanotechnology help the fight against breast cancer?

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Abstract

In this review we provide a broad overview on the use of nanotechnology for the fight against breast cancer (BC). Nowadays, detection, diagnosis, treatment, and prevention may be possible thanks to the application of nanotechnology to clinical practice. Taking into consideration the different forms of BC and the disease status, nanomaterials can be designed to meet the most forefront objectives of modern therapy and diagnosis. We have analyzed in detail three main groups of nanomaterial applications for BC treatment and diagnosis. We have identified several types of drugs successfully conjugated with nanomaterials. We have analyzed the main important imaging techniques and all nanomaterials used to help the non-invasive, early detection of the lesions. Moreover, we have examined theranostic nanomaterials as unique tools, combining imaging, detection, and therapy for BC. This state of the art review provides a useful guide depicting how nanotechnology can be used to overcome the current barriers in BC clinical practice, and how it will shape the future scenario of treatments, prevention, and diagnosis, revolutionizing the current approaches, e.g., reducing the suffering related to chemotherapy.

Graphical abstract: How can nanotechnology help the fight against breast cancer?

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Publication details

The article was received on 07 Apr 2018, accepted on 18 May 2018 and first published on 21 May 2018


Article type: Review Article
DOI: 10.1039/C8NR02796J
Citation: Nanoscale, 2018,10, 11719-11731
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    How can nanotechnology help the fight against breast cancer?

    E. Avitabile, D. Bedognetti, G. Ciofani, A. Bianco and L. G. Delogu, Nanoscale, 2018, 10, 11719
    DOI: 10.1039/C8NR02796J

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