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Low-cost, Flexible and Regular-array Three-dimensional Nanopyramid Antibacterial Films for Clinical Applications

Abstract

In this work, a low-cost, scalable and highly repeatable approach was developed to fabricate polystyrene films with three-dimensional nanopyramids on the surface. The nanopyramids have tubable aspect ratio and more importantly, their anti-bacterial performance has been systematically studied. The effectiveness of the nanopyramids on E. coli growth inhibition and the role of nanostructure aspect ratio were carefully studied through scanning electron microscopy and confocal laser scanning microscopy. The results showed an excellent antibacterial performance with more than 90% reduction in E. coli population in all nanopyramid samples after a 168-hr prolonged incubation time. The nanopyramid film developed here can be used for the clinical and commercial applications to prevent the growth of pathogenic bacteria on various surfaces without using any disinfectant.

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Publication details

The article was received on 17 Mar 2018, accepted on 16 Apr 2018 and first published on 20 Apr 2018


Article type: Paper
DOI: 10.1039/C8NR01968A
Citation: Nanoscale, 2018, Accepted Manuscript
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    Low-cost, Flexible and Regular-array Three-dimensional Nanopyramid Antibacterial Films for Clinical Applications

    K. Tsui, X. Li, J. K. H. Tsoi, S. Leung, T. Lei, W. Y. Chak, C. F. Zhang, J. Chen, C. Gary Shun Pan and Z. Fan, Nanoscale, 2018, Accepted Manuscript , DOI: 10.1039/C8NR01968A

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