Jump to main content
Jump to site search


Deciphering the role of substrate stiffness to enhance internalization efficiency of plasmid DNA in stem cells using lipid-based nanocarriers

Abstract

This study investigates the role of substrate stiffness on non-viral transfection of human adipose-derived stem cells (hASCs) with the aim to maximize hASCs expression of vascular endothelial growth factor (VEGF). The results confirm the direct effect of substrate stiffness in regulating cytoskeletal remodeling and corresponding plasmid internalization.

Back to tab navigation

Supplementary files

Publication details

The article was received on 22 Feb 2018, accepted on 05 Apr 2018 and first published on 06 Apr 2018


Article type: Communication
DOI: 10.1039/C8NR01516C
Citation: Nanoscale, 2018, Accepted Manuscript
  •   Request permissions

    Deciphering the role of substrate stiffness to enhance internalization efficiency of plasmid DNA in stem cells using lipid-based nanocarriers

    S. Modaresi, S. Pacelli, J. Whitlow and A. Paul, Nanoscale, 2018, Accepted Manuscript , DOI: 10.1039/C8NR01516C

Search articles by author

Spotlight

Advertisements