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Metal-ion responsive reversible assembly of DNA origami dimers: G-quadruplex induced intermolecular interaction

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Abstract

We present a novel metal-ion stimulated organization of DNA origami nanostructures by employing G-quadruplexes as stimuli-responsive bridges. The reversible assembly process of DNA origami was the result of conformational changes between the G-quadruplex and its single-strand state induced by monovalent cations. This study might stimulate a new design of responsive DNA-based intelligent nanomaterials.

Graphical abstract: Metal-ion responsive reversible assembly of DNA origami dimers: G-quadruplex induced intermolecular interaction

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Publication details

The article was received on 19 Dec 2017, accepted on 21 Jan 2018 and first published on 22 Jan 2018


Article type: Communication
DOI: 10.1039/C7NR09458B
Citation: Nanoscale, 2018, Advance Article
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    Metal-ion responsive reversible assembly of DNA origami dimers: G-quadruplex induced intermolecular interaction

    S. Yang, W. Liu, R. Nixon and R. Wang, Nanoscale, 2018, Advance Article , DOI: 10.1039/C7NR09458B

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