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Issue 13, 2018
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Polymeric nanorods with aggregation-induced emission characteristics for enhanced cancer targeting and imaging

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Abstract

Polymeric nanorods loaded with AIEgens are synthesized via nano-precipitation under ultrasound sonication, where prolonged sonication time could induce a nanodot-to-nanorod transition. These AIE nanorods, but not the nanodots, could be selectively internalized into cancer cells, which show better tumor accumulation, higher tumor penetration and more efficient in vivo cancer cell uptake.

Graphical abstract: Polymeric nanorods with aggregation-induced emission characteristics for enhanced cancer targeting and imaging

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Publication details

The article was received on 11 Dec 2017, accepted on 01 Mar 2018 and first published on 09 Mar 2018


Article type: Communication
DOI: 10.1039/C7NR09196F
Citation: Nanoscale, 2018,10, 5869-5874
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    Polymeric nanorods with aggregation-induced emission characteristics for enhanced cancer targeting and imaging

    G. Feng, D. Mao, J. Liu, C. C. Goh, L. G. Ng, D. Kong, B. Z. Tang and B. Liu, Nanoscale, 2018, 10, 5869
    DOI: 10.1039/C7NR09196F

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