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Protein-Mediated Anti-Adhesion Surface against Oral Bacteria

Abstract

Biomedical materials, such as orthopedic biomaterials impose a great impact on improving life quality and self-esteem of human beings. However, the usage of fixed appliances during dental treatment often increases the difficulty of oral cleaning and enlarges the adhesion opportunity of oral bacteria. Furthermore, the existing anti-adhesion coatings, such as polyethylene glycol derivatives and zwitterionic polymers, have not universally accepted in oral environment due to their intrinsic problems. Herein, inspired by the anti-adhesion capability of bovine serum albumin, we report a facile protein-based anti-bacteria surface, showing excellent anti adhesion performance toward oral bacteria. This protein-mediated anti-adhesion strategy may provide a promising clue for developing new anti-bacterial biomaterials, such as dental fixed appliances, restorative materials and medical mouthwashes.

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Publication details

The article was received on 27 Nov 2017, accepted on 09 Jan 2018 and first published on 09 Jan 2018


Article type: Communication
DOI: 10.1039/C7NR08844B
Citation: Nanoscale, 2018, Accepted Manuscript
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    Protein-Mediated Anti-Adhesion Surface against Oral Bacteria

    X. Liu, L. Peng, J. Meng, Z. Zhu, B. Han and S. Wang, Nanoscale, 2018, Accepted Manuscript , DOI: 10.1039/C7NR08844B

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