Issue 9, 2018

Halimane diterpenoids: sources, structures, nomenclature and biological activities

Abstract

Covering: 1970 to 2017

Diterpenes with a halimane skeleton constitute a small group of natural products that can be biogenetically considered as being between labdane and clerodane diterpenoids. Some of these compounds show biological activities, such as antitumour, mosquito repellency, germination inhibition and antimicrobial, as well as being biomarkers for tuberculosis. To the best of our knowledge, there are no reviews on these compounds. In this review, halimane skeleton diterpenoids are classified according to their biogenetic origin, characterization and/or the enzymes involved in their biosynthesis. Herein, a review of their synthesis or synthetic approaches is communicated.

Graphical abstract: Halimane diterpenoids: sources, structures, nomenclature and biological activities

Supplementary files

Article information

Article type
Review Article
Submitted
22 Feb 2018
First published
27 Apr 2018
This article is Open Access
Creative Commons BY license

Nat. Prod. Rep., 2018,35, 955-991

Halimane diterpenoids: sources, structures, nomenclature and biological activities

A. M. Roncero, I. E. Tobal, R. F. Moro, D. Díez and I. S. Marcos, Nat. Prod. Rep., 2018, 35, 955 DOI: 10.1039/C8NP00016F

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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