Issue 7, 2018

Unique chemistry of non-heme iron enzymes in fungal biosynthetic pathways

Abstract

Covering: up to 2018

Non-heme iron enzymes are a versatile family of oxygenases that catalyze remarkable types of chemistry. This review highlights the intriguing chemistry of non-heme iron enzymes, especially those utilizing α-ketoglutarate (α-KG) as a co-substrate, in fungal secondary metabolism and aims to summarize how nature diversifies and complexifies natural products.

Graphical abstract: Unique chemistry of non-heme iron enzymes in fungal biosynthetic pathways

Article information

Article type
Review Article
Submitted
19 Nov 2017
First published
07 Mar 2018

Nat. Prod. Rep., 2018,35, 633-645

Unique chemistry of non-heme iron enzymes in fungal biosynthetic pathways

H. Nakamura, Y. Matsuda and I. Abe, Nat. Prod. Rep., 2018, 35, 633 DOI: 10.1039/C7NP00055C

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