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Issue 7, 2018
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Unique chemistry of non-heme iron enzymes in fungal biosynthetic pathways

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Abstract

Covering: up to 2018

Non-heme iron enzymes are a versatile family of oxygenases that catalyze remarkable types of chemistry. This review highlights the intriguing chemistry of non-heme iron enzymes, especially those utilizing α-ketoglutarate (α-KG) as a co-substrate, in fungal secondary metabolism and aims to summarize how nature diversifies and complexifies natural products.

Graphical abstract: Unique chemistry of non-heme iron enzymes in fungal biosynthetic pathways

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Publication details

The article was received on 19 Nov 2017 and first published on 07 Mar 2018


Article type: Review Article
DOI: 10.1039/C7NP00055C
Citation: Nat. Prod. Rep., 2018,35, 633-645
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    Unique chemistry of non-heme iron enzymes in fungal biosynthetic pathways

    H. Nakamura, Y. Matsuda and I. Abe, Nat. Prod. Rep., 2018, 35, 633
    DOI: 10.1039/C7NP00055C

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