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Rhodamine–benzothiazole conjugate as an efficient multimodal sensor for Hg2+ ions and its application to imaging in living cells

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Abstract

A rhodamine B dye bearing a benzothiazole (RBT-1) conjugate is designed and synthesized, it shows a highly selective and sensitive naked-eye color change and turn-on fluorescence response to Hg2+ ions. The detection limit of RBT-1 towards Hg2+ is found to be 0.17 nM. RBT-1 exhibits low cytotoxicity and cell membrane permeability, which makes it capable of sensing Hg2+ in HeLa cells and real water samples.

Graphical abstract: Rhodamine–benzothiazole conjugate as an efficient multimodal sensor for Hg2+ ions and its application to imaging in living cells

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Publication details

The article was received on 12 Apr 2018, accepted on 30 May 2018 and first published on 07 Jun 2018


Article type: Paper
DOI: 10.1039/C8NJ01736K
Citation: New J. Chem., 2018, Advance Article
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    Rhodamine–benzothiazole conjugate as an efficient multimodal sensor for Hg2+ ions and its application to imaging in living cells

    P. Sakthivel, K. Sekar, G. Sivaraman and S. Singaravadivel, New J. Chem., 2018, Advance Article , DOI: 10.1039/C8NJ01736K

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