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Pyrazoline based fluorescent chemosensor for Al3+ ion detection and live cell imaging

Abstract

Two pyrene appended pyrazoline compounds (PY-I and PY-II) were designed and synthesized. Their photophysical properties were studied by absorption and fluorescence spectral studies. The PY-I displays an excellent selective and sensitive response to Al3+ ion over other metal ions, whereas PY-II did not response to any metal ions. A 1:1 stoichiometry for PY-I-Al3+ complex was formed with an association constant of 2.13×103 M-1. Furthermore, PY-I employed for fluorescent imaging of Al3+ ion in living cells. The PY-I has phenolic group as a binding site at 3-position to that of pyrazoline ring responsible for its sensing of metal ion. Nevertheless, PY-II has no hydroxyl group in the phenyl ring and unable to sense the metal ions rather PY-II has good photophysical properties suitable as fluorescent material.

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Publication details

The article was received on 12 Mar 2018, accepted on 22 Apr 2018 and first published on 11 May 2018


Article type: Paper
DOI: 10.1039/C8NJ01211C
Citation: New J. Chem., 2018, Accepted Manuscript
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    Pyrazoline based fluorescent chemosensor for Al3+ ion detection and live cell imaging

    K. Palaninathan and M. -. Rangasamy, New J. Chem., 2018, Accepted Manuscript , DOI: 10.1039/C8NJ01211C

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