Jump to main content
Jump to site search


New strategy for the azido–ascorbic acid reaction: a convenient chemosensor and its imaging in garlic slice tissues

Author affiliations

Abstract

Ascorbic acid (AA) is a vital nutritional factor in many fruits and plants, and abnormal levels of AA are closely associated with several diseases. Therefore, the development of convenient methods for monitoring AA levels in biological systems is of great importance. In this work, we designed and synthesized three chemosensors for the rapid turn-on detection of AA via a new strategy for the azido–ascorbic acid reaction. The chemosensors were based on a 1,8-naphthalimide moiety with the azide group at different sites (probes 1, 2, and 3). The experimental results demonstrated that probe 2 showed high selectivity toward AA, having an experimental limit of detection of 74 nM. Its reduction was easier than that of probe 3 with a 3-substituted azide group. Moreover, probe 2 was successfully used for imaging of AA in garlic slice tissue for the first time.

Graphical abstract: New strategy for the azido–ascorbic acid reaction: a convenient chemosensor and its imaging in garlic slice tissues

Back to tab navigation

Supplementary files

Publication details

The article was received on 02 Feb 2018, accepted on 24 Mar 2018 and first published on 26 Mar 2018


Article type: Paper
DOI: 10.1039/C8NJ00589C
Citation: New J. Chem., 2018, Advance Article
  •   Request permissions

    New strategy for the azido–ascorbic acid reaction: a convenient chemosensor and its imaging in garlic slice tissues

    D. Zhang, N. Li, Y. Ma, R. Wang, J. Wang and J. Wang, New J. Chem., 2018, Advance Article , DOI: 10.1039/C8NJ00589C

Search articles by author

Spotlight

Advertisements