Jump to main content
Jump to site search

Issue 7, 2018
Previous Article Next Article

A sensitive two-photon ratiometric fluorescent probe for γ-glutamyltranspeptidase activity detection and imaging in living cells and cancer tissues

Author affiliations

Abstract

We develop a novel two-photon ratiometric fluorescent probe based on the conjugation of the specific recognition moiety of the γ-glutamyl group to 6-acetyl-2-aminonaphthalene, which enables highly sensitive, selective monitoring of γ-glutamyltransferase activities in human serum and imaging in living cells and cancer tissues down to a depth of 120 μm.

Graphical abstract: A sensitive two-photon ratiometric fluorescent probe for γ-glutamyltranspeptidase activity detection and imaging in living cells and cancer tissues

Back to tab navigation

Supplementary files

Publication details

The article was received on 30 Jan 2018, accepted on 22 Feb 2018 and first published on 28 Feb 2018


Article type: Paper
DOI: 10.1039/C8NJ00520F
Citation: New J. Chem., 2018,42, 5403-5407
  •   Request permissions

    A sensitive two-photon ratiometric fluorescent probe for γ-glutamyltranspeptidase activity detection and imaging in living cells and cancer tissues

    W. Liu, B. Huang, Z. Tong, S. Wang, Y. Li and Y. Dai, New J. Chem., 2018, 42, 5403
    DOI: 10.1039/C8NJ00520F

Search articles by author

Spotlight

Advertisements