Jump to main content
Jump to site search


Photocleavable antimicrobial peptide mimics for precluding antibiotic resistance

Author affiliations

Abstract

Cationic amphiphiles featuring a lysine-based hydrophilic moiety, an alkyl chain-based hydrophobic moiety, and an o-nitrobenzyl group-based linker were constructed facilely, which show alkyl chain-dependent antibacterial activity against both Gram-positive and Gram-negative bacteria, low cytotoxicity toward mammalian cells, and UV-cleavable properties, representing a novel type of environmental accumulation-free antimicrobial peptide mimic.

Graphical abstract: Photocleavable antimicrobial peptide mimics for precluding antibiotic resistance

Back to tab navigation

Supplementary files

Publication details

The article was received on 02 Jan 2018, accepted on 30 Jan 2018 and first published on 31 Jan 2018


Article type: Letter
DOI: 10.1039/C8NJ00015H
Citation: New J. Chem., 2018, Advance Article
  •   Request permissions

    Photocleavable antimicrobial peptide mimics for precluding antibiotic resistance

    Y. Feng, Y. Zhang, K. Li, N. Tian, W. Wang, Q. Zhou and X. Wang, New J. Chem., 2018, Advance Article , DOI: 10.1039/C8NJ00015H

Search articles by author

Spotlight

Advertisements