Issue 5, 2018

Ethyl acetate fraction of Cymbopogon citratus as a potential source of antioxidant compounds

Abstract

This study aimed to characterize different extracts/fractions obtained from Cymbopogon citratus according to their chemical composition and antioxidant properties. Plant leaves were submitted to extractions with different solvents, and the antioxidant capability of each fraction was analyzed using different methods (E1–E4). The ethyl acetate fraction from extraction procedure 1 (E1) presented a high polyphenolic content and antioxidant capability. Therefore, in E2, the pH of the aqueous phases was modified to fractionate the compounds in the ethyl acetate extractions. Interestingly, the fraction obtained at pH 4 presented a higher antioxidant activity than AcOEt F1. Furthermore, it was verified that the essential oil removal improved the extraction of polyphenols in ethyl acetate fractions. The antioxidant activity of these fractions was comparable to ascorbic acid, and could also inhibit TBARS production in phospholipids comparatively to vitamin E. Such fraction will be further explored to isolate the active chemicals, and to evaluate its toxicity and antioxidant actions in vivo.

Graphical abstract: Ethyl acetate fraction of Cymbopogon citratus as a potential source of antioxidant compounds

Supplementary files

Article information

Article type
Paper
Submitted
09 Nov 2017
Accepted
17 Jan 2018
First published
08 Feb 2018

New J. Chem., 2018,42, 3642-3652

Ethyl acetate fraction of Cymbopogon citratus as a potential source of antioxidant compounds

A. C. M. Hacke, J. A. Marques, J. C. R. Vellosa, A. A. Boligon, F. D. da Silva, D. de Souza, J. S. Bonini, J. B. T. Rocha and R. P. Pereira, New J. Chem., 2018, 42, 3642 DOI: 10.1039/C7NJ04352J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements