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Issue 2, 2018
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A novel ESIPT-based fluorescent chemodosimeter for Hg2+ detection and its application in live-cell imaging

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Abstract

A new excited-state intramolecular proton transfer (ESIPT) based fluorescent chemodosimeter for the detection of Hg2+ has been rationally designed and developed. The probe operates via the specific mercury-promoted desulfurization reaction of thiophthalimide to phthalimide and exhibits high selectivity and sensitivity in an almost pure aqueous solution (containing only 1% DMSO) with a low detection limit of 1.5 ppb. Furthermore, the probe was successfully used for the fluorescence imaging of Hg2+ in live cells.

Graphical abstract: A novel ESIPT-based fluorescent chemodosimeter for Hg2+ detection and its application in live-cell imaging

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Publication details

The article was received on 05 Oct 2017, accepted on 07 Dec 2017 and first published on 08 Dec 2017


Article type: Paper
DOI: 10.1039/C7NJ03789A
Citation: New J. Chem., 2018,42, 1181-1186
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    A novel ESIPT-based fluorescent chemodosimeter for Hg2+ detection and its application in live-cell imaging

    J. Huang, B. Chen, B. Zhou and Y. Han, New J. Chem., 2018, 42, 1181
    DOI: 10.1039/C7NJ03789A

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