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Schiff base receptor as fluorescence turn-on sensor for Ni2+ ions in live cells and logic gate application

Abstract

A new, easily available “off-on-off” colorimetric and fluorescent receptor (R) was synthesized and characterized using 1H NMR, 13C NMR and ESI-MS studies. It exhibited selective and sensitive detection towards Ni2+ ion without having any interference from other tested metal ions. The obtained photophysical changes are due to the process if the ligand to metal charge transfers (LMCT) and chelation enhanced fluorescence effect (CHEF) after addition of Ni2+ to the receptor. Density Functional Theory (DFT) calculations were theoretically supported the examined absorption and fluorescence spectral changes. Moreover, receptor could be successfully oriented with molecular logic functions of OR, AND, NOR and NOT gates. Furthermore, the receptor efficacy was studied by examined changes in intracellular Ni2+ in HeLa cells. The receptor has been exposed to be a possible application for real sample analysis and test kit for the detection of Ni2+.

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Publication details

The article was received on 04 Oct 2017, accepted on 10 Jan 2018 and first published on 11 Jan 2018


Article type: Paper
DOI: 10.1039/C7NJ03784H
Citation: New J. Chem., 2018, Accepted Manuscript
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    Schiff base receptor as fluorescence turn-on sensor for Ni2+ ions in live cells and logic gate application

    G. G. Vinoth Kumar, K. Mookkandi Palsamy, S. Murugesan , K. Sakthipandi, R. Jegathalaprathaban and S. gandhi, New J. Chem., 2018, Accepted Manuscript , DOI: 10.1039/C7NJ03784H

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