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Microwave-assisted MgO NP catalyzed one-pot multicomponent synthesis of polysubstituted steroidal pyridines

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Abstract

The present study reports a highly efficient and green synthetic route for the synthesis of steroidal pyridines. The synthetic methodology involves a microwave-assisted one-pot multicomponent reaction using MgO NPs as a heterogeneous, mild and reusable catalyst. The synthesized MgO NPs were characterized by FTIR, TGA/DTA and XRD analyses. The remarkable features of this protocol include simple operational procedure, shorter reaction profiles, mild reaction conditions, minimal chemical waste and economic viability. The recyclability of the catalyst and high yield of products make the proposed method a sustainable alternative.

Graphical abstract: Microwave-assisted MgO NP catalyzed one-pot multicomponent synthesis of polysubstituted steroidal pyridines

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Publication details

The article was received on 30 Sep 2017, accepted on 17 Nov 2017 and first published on 20 Nov 2017


Article type: Paper
DOI: 10.1039/C7NJ03742B
Citation: New J. Chem., 2018, Advance Article
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    Microwave-assisted MgO NP catalyzed one-pot multicomponent synthesis of polysubstituted steroidal pyridines

    A. Ansari, A. Ali, M. Asif and Shamsuzzaman, New J. Chem., 2018, Advance Article , DOI: 10.1039/C7NJ03742B

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