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Transition Metal Free Oxygenation of 8-Aminoquinoline Amides in Water

Abstract

The oxygenation of 8-aminoquinoline amides by benzoyl peroxide at the C5 position in water is developed in the absence of transition metal catalyst, affording the desired products in moderate to good yields up to 88%. Mechanism studies reveal that the reaction would involve a radical process.

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Publication details

The article was received on 18 Jan 2018, accepted on 12 Apr 2018 and first published on 13 Apr 2018


Article type: Communication
DOI: 10.1039/C8GC00191J
Citation: Green Chem., 2018, Accepted Manuscript
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    Transition Metal Free Oxygenation of 8-Aminoquinoline Amides in Water

    X. Zhou, X. Yao, X. Weng, K. Wang and H. Xiang, Green Chem., 2018, Accepted Manuscript , DOI: 10.1039/C8GC00191J

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