Jump to main content
Jump to site search

Issue 3, 2018
Previous Article Next Article

Metal-free regioselective hydrochlorination of unactivated alkenes via a combined acid catalytic system

Author affiliations

Abstract

A combined acid HCl/DMPU-acetic acid catalytic system was used in the hydrochlorination of a wide range of unactivated alkenes. This hydrochlorination strategy is remarkably greener than previous reported methods in terms of high atom efficiency, no toxic waste generated and metal-free process. The higher efficiency, compared with other commercially available HCl reagents, was augmented by the good regioselectivity and functionality tolerance found. A stepwise mechanism for this hydrochlorination process was proposed based on kinetic studies.

Graphical abstract: Metal-free regioselective hydrochlorination of unactivated alkenes via a combined acid catalytic system

Back to tab navigation

Supplementary files

Publication details

The article was received on 06 Dec 2017, accepted on 31 Dec 2017 and first published on 02 Jan 2018


Article type: Paper
DOI: 10.1039/C7GC03665E
Citation: Green Chem., 2018,20, 680-684
  •   Request permissions

    Metal-free regioselective hydrochlorination of unactivated alkenes via a combined acid catalytic system

    S. Liang, G. B. Hammond and B. Xu, Green Chem., 2018, 20, 680
    DOI: 10.1039/C7GC03665E

Search articles by author

Spotlight

Advertisements