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Zinc Oxide-NP Catalysed Direct Indolation of in situ generated Bioactive Tryptanthrin

Abstract

A ZnO-NP catalyzed direct indolation of in situ generated tryptanthrin via C-H functionalization and C-C bond formation has been developed. This novel and greener approach have been effectively utilized to accomplish the synthesis of 6-hydroxy-6-(1H-indol-3-yl)indolo[2,1-b] quinazolin-12(6H)-one derivatives in good to excellent yield with high product selectivity. Besides, in situ approach a direct indolation of tryptanthrin has also been developed.

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Publication details

The article was received on 20 Nov 2017, accepted on 01 Jan 2018 and first published on 03 Jan 2018


Article type: Communication
DOI: 10.1039/C7GC03479B
Citation: Green Chem., 2018, Accepted Manuscript
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    Zinc Oxide-NP Catalysed Direct Indolation of in situ generated Bioactive Tryptanthrin

    A. Kumar, B. Rai and R. D. Shukla, Green Chem., 2018, Accepted Manuscript , DOI: 10.1039/C7GC03479B

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