Jump to main content
Jump to site search

Issue 7, 2018
Previous Article Next Article

Quality assessment of Penthorum chinense Pursh through multicomponent qualification and fingerprint, chemometric, and antihepatocarcinoma analyses

Author affiliations

Abstract

An efficient method combined with fingerprint and chemometric analyses was developed to evaluate the quality of the traditional Chinese medicine plant Penthorum chinense Pursh. Nine samples were collected from different regions during different harvest periods, and 17 components in the form of extracts were simultaneously examined to assess quality by using high-performance liquid chromatography. The hepatoprotective effects of components were investigated by assessing the inhibition of SMMC-7721 cell growth. The results indicated that the quality control method was accurate, stable, and reliable, and the hierarchical heat-map cluster and the principle component analyses confirmed that the classification of all nine samples was consistent. Quercetin and ellagitannins including pinocembrin-7-O-[3′′-O-galloyl-4′′,6′′-hexahydroxydiphenoyl]-β-glucose (PGHG), thonningianin A, thonningianin B, and other flavonoids were abundant in the extracts, and significantly contributed to the hepatoprotective effects.

Graphical abstract: Quality assessment of Penthorum chinense Pursh through multicomponent qualification and fingerprint, chemometric, and antihepatocarcinoma analyses

Back to tab navigation

Supplementary files

Publication details

The article was received on 19 Apr 2018, accepted on 29 May 2018 and first published on 31 May 2018


Article type: Paper
DOI: 10.1039/C8FO00754C
Citation: Food Funct., 2018,9, 3807-3814
  •   Request permissions

    Quality assessment of Penthorum chinense Pursh through multicomponent qualification and fingerprint, chemometric, and antihepatocarcinoma analyses

    Z. Sun, Y. Zhang, F. Zhang, J. Zhang, G. Zheng, L. Tan, C. Wang, L. Zhou, Q. Zhang and C. Yuan, Food Funct., 2018, 9, 3807
    DOI: 10.1039/C8FO00754C

Search articles by author

Spotlight

Advertisements