Jump to main content
Jump to site search

Issue 8, 2018
Previous Article Next Article

Photochemical detoxification of Cr(VI) using iron and saccharic acid: insights from cytotoxic and genotoxic assays

Author affiliations

Abstract

Herein, we demonstrate rapid and complete photochemical detoxification of Cr(VI) by iron using saccharic acid (SA) as a sacrificial organic agent. 100% Cr(VI) (200 μM) was reduced within 30 min using Fe(III) (50 μM) and SA (300 μM) under UV irradiation. The reaction mechanism involves photochemical recycling of Fe(III)/Fe(II) by SA via ligand to metal charge transfer (LMCT) along with the generation of a concomitant ligand radical and hydroperoxyl radical. Importantly, the MTT assay and γH2AX immunostaining were performed to evaluate the hitherto unexplored comparison of cytotoxicity and genotoxicity caused by untreated and treated aqueous Cr(VI). The results revealed that the Fe(III)/SA/UV treatment caused the complete removal of cytotoxic and genotoxic effects of Cr(VI) towards human cell lines. The presence of nitrate, chloride and natural organic matter increased the Cr(VI) reduction, while phosphate decreased the Cr(VI) reduction. Cu(II), Al(III) and Ni(II) had a positive effect on the Cr(VI) reduction. Furthermore, the Fe(III)/SA/UVC treatment caused almost complete Cr(VI) reduction in groundwater, lake water, and simulated galvanic wastewater. This study strongly supports the aptness of the Fe(III)/SA photochemical system for detoxification of Cr(VI) contaminated wastewater.

Graphical abstract: Photochemical detoxification of Cr(vi) using iron and saccharic acid: insights from cytotoxic and genotoxic assays

Back to tab navigation

Supplementary files

Publication details

The article was received on 06 Apr 2018, accepted on 01 Jun 2018 and first published on 04 Jun 2018


Article type: Paper
DOI: 10.1039/C8EW00216A
Citation: Environ. Sci.: Water Res. Technol., 2018,4, 1152-1162
  •   Request permissions

    Photochemical detoxification of Cr(VI) using iron and saccharic acid: insights from cytotoxic and genotoxic assays

    G. Subramanian, G. S. S. Kumar, V. Ravi, N. R. Sundaresan and G. Madras, Environ. Sci.: Water Res. Technol., 2018, 4, 1152
    DOI: 10.1039/C8EW00216A

Search articles by author

Spotlight

Advertisements