Jump to main content
Jump to site search


Co-crystals and Salts of Vanillic Acid and Vanillin with Amines

Abstract

Vanillin (VAN) and its oxidized form vanillic acid (VA) have successfully formed a series of co-crystals and salts. VAN formed a co-crystal with isonicotinamide (INM) and a co-crystal hydrate with theobromine (THB). Binary co-crystals with isonicotinamide (INM), hexamine (HEXA), phenazine (PHZ) and pyrazine-n-oxide (PZO) were obtained with VA. Interestingly, a ternary co-crystal resulted from a 1: 1: 1 ratio of VA, caffeine (CAF) and nicotinamide (NAM). Salt hydrates were also formed between piperazine (PPZ) and 1,4-diazabicyclo[2.2.2]octane (DABCO) with VA. All co-crystals and salts were characterized by x-ray diffraction techniques, thermal analysis, and Infrared spectroscopy.

Back to tab navigation

Supplementary files

Publication details

The article was received on 22 Nov 2017, accepted on 05 Jan 2018 and first published on 08 Jan 2018


Article type: Paper
DOI: 10.1039/C7CE02022H
Citation: CrystEngComm, 2018, Accepted Manuscript
  •   Request permissions

    Co-crystals and Salts of Vanillic Acid and Vanillin with Amines

    F. M. Amombo Noa and G. Mehlana, CrystEngComm, 2018, Accepted Manuscript , DOI: 10.1039/C7CE02022H

Search articles by author

Spotlight

Advertisements