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Issue 3, 2018
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Cocrystal structure design for CH5134731 based on isomorphism

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Abstract

We succeeded in forming a benzoic acid cocrystal of CH5134731 by focusing on the isomorphism shown by its solvates. As a result of evaluation, the benzoic acid cocrystal showed good solubility. This crystal engineering approach made it possible to reduce the amount of compound and study time in the early stage of research and development.

Graphical abstract: Cocrystal structure design for CH5134731 based on isomorphism

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Publication details

The article was received on 30 Oct 2017, accepted on 09 Dec 2017 and first published on 11 Dec 2017


Article type: Paper
DOI: 10.1039/C7CE01878A
Citation: CrystEngComm, 2018,20, 362-369
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    Cocrystal structure design for CH5134731 based on isomorphism

    S. Tanida, N. Takata, R. Takano, A. Sakon, T. Ueto, K. Shiraki, K. Kadota, Y. Tozuka and M. Ishigai, CrystEngComm, 2018, 20, 362
    DOI: 10.1039/C7CE01878A

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