Issue 87, 2018

p-Toluenesulfonic acid catalysed fluorination of α-branched ketones for the construction of fluorinated quaternary carbon centres

Abstract

A p-toluenesulfonic acid catalyzed fluorination of α-branched ketones for the construction of fluorinated quaternary carbon centers has been developed, featuring a broad substrate scope, environmentally benign reaction conditions, and operational simplicity.

Graphical abstract: p-Toluenesulfonic acid catalysed fluorination of α-branched ketones for the construction of fluorinated quaternary carbon centres

Supplementary files

Article information

Article type
Communication
Submitted
15 Aug 2018
Accepted
09 Oct 2018
First published
09 Oct 2018

Chem. Commun., 2018,54, 12377-12380

p-Toluenesulfonic acid catalysed fluorination of α-branched ketones for the construction of fluorinated quaternary carbon centres

S. Tang, H. Bian, Z. Zhan, M. Chen, J. Lv, S. Xie and F. Zhang, Chem. Commun., 2018, 54, 12377 DOI: 10.1039/C8CC06643D

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