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Issue 55, 2018
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A cocktail of 165Er(III) and Gd(III) complexes for quantitative detection of zinc using SPECT and MRI

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Abstract

We propose quantitative assessment of zinc by combining nuclear and MR imaging. We use a cocktail of a Gd3+-complex providing a Zn2+-dependent MRI response and its 165Er3+ analogue allowing for concentration assessment. 165Er is readily obtained in a cyclotron and purified, which is indispensable for successful quantification of metal ions.

Graphical abstract: A cocktail of 165Er(iii) and Gd(iii) complexes for quantitative detection of zinc using SPECT and MRI

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Publication details

The article was received on 26 Apr 2018, accepted on 16 May 2018 and first published on 16 May 2018


Article type: Communication
DOI: 10.1039/C8CC03407A
Citation: Chem. Commun., 2018,54, 7597-7600
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    A cocktail of 165Er(III) and Gd(III) complexes for quantitative detection of zinc using SPECT and MRI

    K. P. Malikidogo, I. Da Silva, J. Morfin, S. Lacerda, L. Barantin, T. Sauvage, J. Sobilo, S. Lerondel, É. Tóth and C. S. Bonnet, Chem. Commun., 2018, 54, 7597
    DOI: 10.1039/C8CC03407A

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