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Issue 48, 2018
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Logic circuit controlled multi-responsive branched DNA scaffolds

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Abstract

A logic circuit controlled multi-responsive sensing platform built on a three-way DNA junction (TWJ) is reported. It enabled the construction of novel fluorescent sensing platforms responsive to any target out of HIV gene, ATP and pH value, and furthermore were logically regulated by two other targets and then behaved as different logic circuits, which consist of two tandem AND gates or cascaded NAND and INH gates by varying the positions of the fluorescent tags.

Graphical abstract: Logic circuit controlled multi-responsive branched DNA scaffolds

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Publication details

The article was received on 26 Apr 2018, accepted on 16 May 2018 and first published on 17 May 2018


Article type: Communication
DOI: 10.1039/C8CC03387K
Citation: Chem. Commun., 2018,54, 6132-6135
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    Logic circuit controlled multi-responsive branched DNA scaffolds

    Y. Du, P. Peng and T. Li, Chem. Commun., 2018, 54, 6132
    DOI: 10.1039/C8CC03387K

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