Jump to main content
Jump to site search

Issue 50, 2018
Previous Article Next Article

Design of functionalized cyclic peptides through orthogonal click reactions for cell culture and targeting applications

Author affiliations

Abstract

An approach for the design of functionalized cyclic peptides is established for use in 3D cell culture and in cell targeting. Sequential orthogonal click reactions, specifically a photoinitiated thiol–ene and strain promoted azide–alkyne cycloaddition, were utilized for peptide cyclization and conjugation relevant for biomaterial and biomedical applications, respectively.

Graphical abstract: Design of functionalized cyclic peptides through orthogonal click reactions for cell culture and targeting applications

Back to tab navigation

Supplementary files

Publication details

The article was received on 27 Apr 2018, accepted on 24 May 2018 and first published on 29 May 2018


Article type: Communication
DOI: 10.1039/C8CC03218A
Citation: Chem. Commun., 2018,54, 6923-6926
  •   Request permissions

    Design of functionalized cyclic peptides through orthogonal click reactions for cell culture and targeting applications

    P. J. LeValley, E. M. Ovadia, C. A. Bresette, L. A. Sawicki, E. Maverakis, S. Bai and A. M. Kloxin, Chem. Commun., 2018, 54, 6923
    DOI: 10.1039/C8CC03218A

Search articles by author

Spotlight

Advertisements