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Issue 50, 2018
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Improving metabolome coverage and data quality: advancing metabolomics and lipidomics for biomarker discovery

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Abstract

This Feature Article highlights some of the key challenges within the field of metabolomics and examines what role separation and analytical sciences can play to improve the use of metabolomics in biomarker discovery and personalized medicine. Recent progress in four key areas is highlighted: (i) improving metabolite coverage, (ii) developing accurate methods for unstable metabolites including in vivo global metabolomics methods, (iii) advancing inter-laboratory studies and reference materials and (iv) improving data quality, standardization and quality control of metabolomics studies.

Graphical abstract: Improving metabolome coverage and data quality: advancing metabolomics and lipidomics for biomarker discovery

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Publication details

The article was received on 30 Mar 2018, accepted on 23 May 2018 and first published on 23 May 2018


Article type: Feature Article
DOI: 10.1039/C8CC02592D
Citation: Chem. Commun., 2018,54, 6728-6749
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    Improving metabolome coverage and data quality: advancing metabolomics and lipidomics for biomarker discovery

    D. Vuckovic, Chem. Commun., 2018, 54, 6728
    DOI: 10.1039/C8CC02592D

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