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Issue 38, 2018
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Copper-catalyzed carbonylative transformations of indoles with hexaketocyclohexane

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Abstract

With hexaketocyclohexane octahydrate as the carbon monoxide source, a novel procedure for copper-catalyzed direct double carbonylation of indoles has been established. Using alcohols as reaction partners, moderate to good yields of the desired double carbonylation products have been obtained. Wide functional group tolerance and substrate scope can be observed.

Graphical abstract: Copper-catalyzed carbonylative transformations of indoles with hexaketocyclohexane

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Publication details

The article was received on 05 Mar 2018, accepted on 17 Apr 2018 and first published on 17 Apr 2018


Article type: Communication
DOI: 10.1039/C8CC01784K
Citation: Chem. Commun., 2018,54, 4798-4801
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    Copper-catalyzed carbonylative transformations of indoles with hexaketocyclohexane

    Z. Wang, Z. Yin and X. Wu, Chem. Commun., 2018, 54, 4798
    DOI: 10.1039/C8CC01784K

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